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THCV and Medical Marijuana

Is THCV the Next Wonder Cannabinoid?

I had never even heard of THCV until a member of the Illinois Medical Cannabis Community (IMCC) mentioned it in a post, asking for information. It was intriguing, so I looked into it and here’s what I found out.

THCV is a little-known cannabinoid superstar described as “packing an amazing high, but without the munchies.” Not much research has been done on it, but it is starting to get the recognition it deserves. It’s been known cousin, THC, has been getting all the attention since the 1960s. The two cannabinoids are very similar in chemical make-up. The difference is that THCV is missing a few carbon atoms.

As many of you probably know, THC activates the CB1 receptors in the brain which accounts for its psychoactive qualities. Is THCV also psychoactive, you may ask? Research indicates that it depends on the dosage. At lower doses, THCV acts as a CB1 antagonist, thereby producing no psychoactive effects. However, at larger doses, it can switch and behave like a CB1 agonist, much like THC. But, the THCV high sets in very quickly yet dissipates in about half the time.

In terms of its medicinal benefits, THCV seems to act a bit like CBD in its ability to counteract the psychoactive effects of THC. It has been described as an energetic, clear headed, stimulating buzz. It can also suppress the appetite, food consumption and facilitate weight loss. Testing in mice suggest that that THCV doesn’t completely turn off hunger, but it does seem to improve insulin resistance. It may be useful for those with diabetes.

It also reduces anxiety attacks in those with PTSD without increasing any other symptoms. It improves tremors and motor control in Alzheimer’s Disease patients and stimulates growth of bone cells. It may be an anti-inflammatory.

Since it is a minor cannabinoid, it is found in most strains at trace levels. Certain African strains, particularly landrace sativas, are now known to contain slightly higher concentrations of THCV. Researchers are currently working to produce strains with higher concentrations.

The following strains are known to contain higher concentrations of THCV:

  • Power Plant
  • Willie Nelson
  • Red Congolese
  • Jack the Ripper
  • Durban Cheese
  • Skunk #1
  • Cherry Pie
  • Pineapple Purps – contains higher levels
  • Doug’s Varin
  • Durban Poison – contains small amounts

Be sure to ask your budtender for lab-testing of these strains in order to know how much THCV they contain.

FYI: For those who use vaporizers; THCV has a boiling point of 428F (220C). You need to turn your vaporizer setting up higher than the one you use for THC.

Please feel free to leave your comments if you already use THCV strains while the rest of us catch up!

Source: Ben Adlin Is THCV Psychoactive? Bailey Rahn What is THCV & What Are the Benefits of This Cannabinoid?


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